INCORPORATING MULTI-STAGE DIAGNOSIS STATUS TO MINE ASSOCIATIONS BETWEEN GENETIC RISK VARIANTS AND THE MULTI-MODALITY PHENOTYPE NETWORK IN MAJOR DEPRESSIVE DISORDER

Depression (major depressive disorder, MDD) is a common and serious medical illness.Globally, it is estimated that 5% of adults suffer from depression.Recently, imaging genetics receives growing attention and become a powerful strategy for discoverying the associations between genetic variants (e.g., single-nucleotide polymorphisms, SNPs) and multi

Abstract The paper identifies the key LIVER SUPPORT factors limiting the effectiveness of current public policies to reduce Brazilian Amazon fires.Among them, (i) the dominant allocation of budget to fire suppression in detriment of prevention, (ii) the geographical limitation of the federal action and the reduced policy making capacity of states a

Background: Gestational diabetes mellitus (GDM) represents the state of carbohydrate intolerance during gestation.GDM is found as a risk factor for adverse outcomes of gestation concerning maternal and fetal health conditions.Increasing maternal age is found associated with GDM and also other obstetric complications.High maternal weight is reported

In relation to their posture limitations stroke patients have difficulties in maintaining balance and this is reflected in gait performance which strongly affects independence in Knife Sharpening Steels performing daily living activities.In this framework, the use of virtual reality devices may be helpful as it offers neuroplastic changes in stroke